Sumir Kumar1, Ravinder Garg2, Simmi Aggarwal3, Jaskanwal Kaur1
1Department of Dermatology, GGS Medical College and Hospital, Faridkot, Punjab, India.
2Department of Medicine, GGS Medical College and Hospital, Faridkot, Punjab, India.
3Department of Radiodiagnosis, GGS Medical College and Hospital, Faridkot, Punjab, India.
Isolated cutaneous sarcoidosis is a rare multisystemic granulomatous disorder of unknown etiology. Cutaneous lesions have been classified into specific and nonspecific depending on the presence of noncaseating granulomas on histopathologic studies. Macrophages most likely initiate the response of sarcoidosis by presenting unidentified antigens to CD4+ lymphocytes. A persistent poorly degradable antigen-driven CMI response leads to cytokine cascade, granulomaformation, and fibrosis. In the present study, we report a case of isolated cutaneous sarcoidosis, localized to the face, in an adolescent girl without systemic manifestations which is a rare entity.
Keywords: Cutaneous, facial, sarcoidosis.