Anti-ageing effect of Pandanus tectorius’ seed extract on D-galactose induced ageing mouse model

Authors

  • Sri Endarti Rahayu Faculty of Biology, Universitas Nasional, Jl. Sawo Manila no. 61, Pasar Minggu , South Jakarta 12520, Indonesia
  • Luh Ade Lela Arika Faculty of Biology, Universitas Nasional, Sawo Manila 61 Pasar Minggu South Jakarta 12520 Indonesia
  • Puput Putuh Anisa Faculty of Biology, Universitas Nasional, Sawo Manila 61 Pasar Minggu South Jakarta 12520 Indonesia
  • Suprihatin Faculty of Biology, Universitas Nasional, Sawo Manila 61 Pasar Minggu South Jakarta 12520 Indonesia

Keywords:

superoxide dismutase, malondialdehyde, Pandanus tectorius, skin collagen, phenolic compound

Abstract

The anti-ageing effect of Pandanus tectorius’ seed extract (PTSE) on  D-galactose induced ageing mice and its mechanism was examined in this study. The biochemical and histological analysis of skin tissues showed that PTSE could effectively improve the antioxidant enzyme activity of the ageing mice. In addition, it could enhance the activity of superoxide dismutase (SOD) and decrease the malondialdehyde (MDA) content. Besides, PTSE could maintain the skin collagen, and its effect was found not less than that of the well-known vitamin C. The therapeutic properties of PTSE may possibly be attributed to the phenolic compound present in it. Overall, these results seem to be implying that PTSE is a potential natural anti-skin ageing agent with great antioxidant ability.

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Published

2023-01-12

Issue

Vol. 13 No. 2 (2022): JNatScBiolMed, Vol 13, Issue 2, 2022

Section

Original Article