ABSTRACT

The anti-ageing effect of Pandanus tectorius’ seed extract (PTSE) on  D-galactose induced ageing mice and its mechanism was examined in this study. The biochemical and histological analysis of skin tissues showed that PTSE could effectively improve the antioxidant enzyme activity of the ageing mice. In addition, it could enhance the activity of superoxide dismutase (SOD) and decrease the malondialdehyde (MDA) content. Besides, PTSE could maintain the skin collagen, and its effect was found not less than that of the well-known vitamin C. The therapeutic properties of PTSE may possibly be attributed to the phenolic compound present in it. Overall, these results seem to be implying that PTSE is a potential natural anti-skin ageing agent with great antioxidant ability.