• Maha H. Al-Bahrani, Mohanad S. Al-Fayyadh, Kefah H. Ismeal
  • Department of Molecular and Medical Biotechnology, College of Biotechnology, Al-Nahrain university , Baghdad, Iraq.
  • Email: Maha.albahrani@nahrainuniv.edu.iq.
  • Department of Biotechnology, College of Science, Univ. of Baghdad, Baghdad, Iraq.
  • Email: Mohanad.Majeed@sc.uobaghdad.edu.iq.
  • Department of Chemistry, College of Science, Univ. of Baghdad, Baghdad, Iraq.
  • Email: Kefah.h@sc.uobaghdad.edu.iq.


High carbohydrate diet was incorporated into typical Iraqi food and was given for 35 days to 27 healthy volunteers (males and females). The biochemical parameters including glucose, insulin, urea, creatinine, lipid profile, cortisol and HOMA-IR were analyzed before and after the experiment period. The results depicted significant rise in levels of triglycerides, total cholesterol, low density lipoprotein, and very low-density lipoprotein and significant decline in high density lipoprotein due to high carbohydrate diet (P ≤ 0.05). Furthermore, the plasma insulin, fasting blood sugar, cortisol, HOMA-IR, creatinine, and urea were significantly increased. These findings show that high carbohydrate diets alter insulin, triglycerides, and high density lipoprotein cholesterol levels, which have been linked to an increase in the prevalence of coronary artery disease.

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