ABSTRACT

This study aimed to explore the individual effect of allylestrenol tablets in the treatment of threatened abortion of twin pregnancy and delayed delivery of a second child. A pregnant woman with a threatened abortion of twin pregnancy and delayed delivery of a second child in our hospital was retrospectively analyzed and treated with allylestrenol tablets, and the biochemical indicators of pregnant women and the fetal situation before and after treatment were compared. The results showed that with the increase in pregnancy, the biparietal diameter (BPD) and femur length (FL) were notably increased, the amniotic fluid index (AFI) was drastically decreased (P < 0.05), and the white blood cell count (WBC), platelet count (PLT), and fibrinogen (FIB) were notably increased. Red blood cell count (RBC) and high sensitivity C-reactive protein (hs-CRP) was drastically decreased (P < 0.05). Furthermore, the levels of progesterone (P) and estradiol (E₂) in pregnant women with threatened abortion and delayed delivery of twin pregnancy were notably increased after treatment (P < 0.05). After treatment, the levels of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in pregnant women with threatened abortion and delayed delivery of the second child in twin pregnancy were drastically decreased (P < 0.05). However, there was no considerable difference in fetal birth weight or fetal Apgar score (P > 0.05). In conclusion, allylestrenol tablets have shown positive effect in the treatment of threatened abortion and delayed delivery of twin pregnancy.