ABSTRACT

Thalassemia is a hereditary disease caused by a mutation in the globin gene, resulting in anemia as a risk factor for patients' lives. There are different types of mutations in the globin gene. Despite the types of mutations differing from area to area due to migration and traditions between worlds, there is a need to recognize these different mutations in order to control the disease, and to identify the spectrum of the most common mutations and the relationship between these mutations and the severity of the disease.