ABSTRACT

Background: Heart failure (HF) is a serious and expanding medical condition for which there are still difficulties in managing comorbidity, non-adherence to therapy, and the coexistence of consequences. Numerous studies have attempted to decrease the rate of hospitalization among patients with HF by using an all-encompassing and multidisciplinary strategy, whereas medication compliance was rarely measured. Aim of Study: To evaluate the effect of pharmacist care on patient outcomes in heart failure (HF). We aimed to ascertain how a pharmacist-led intervention affected heart failure patients’ adherence to their prescription regimens. Methodology: We investigated the effect of a pharmacist-led intervention on medication compliance in heart failure patients who were admitted to Jordanian hospitals or who showed up at an outpatient cardiology clinic while using loop diuretics (This is inclusion criteria for study). A randomized controlled trial was used for the investigation. Over six months, patients in the intervention group saw their community pharmacist once a month. The control group’s patients got standard care. A digital tablet bottle that records the opening moment was used to assess the medication event monitoring system. Furthermore, data on the number of readmissions, deaths, and life expectancy were obtained. 200 patients were randomized; 102 were placed in the intervention group and 98 in the control group, receiving standard care. Results: During the six-month study time frame, individuals in the usual care group took loop diuretics for 335/6191 days (the relative risk was 0.31 [confidence interval (CI) 95% 0.23–0.39]), compared to 145/7651 days for patients in the intervention group. Conclusion: Even in case of individuals with relatively high compliance, a pharmacy-led approach can further increase medication compliance specially with those patients who are suffering with moderate to severe HF. Pharmacist care in the treatment of patients with HF greatly reduces the risk of all-cause and HF hospitalisations. Less compliant patients should also be the focus of future interventions