Elena Vladimirovna Maksimenko, Anna Vladimirovna Lekar, Salima Salimovna Khizrieva, Sergey Nikolaevich Borisenko, Elena Vladimirovna Vetrova, Nikolay Ivanovich Borisenko, Vladimir Isaakovich Minkin.
Laboratory of Critical Fluid Technologies, Institute of Physical and Organic Chemistry, Southern Federal University, Stachky Avenue 194/2, Rostov-on-Don, Russian Federation, Russia.
DOI: 10.4103/jnsbm.JNSBM_161_17


This work is aimed at the development of an “one-pot” technique for the production of the natural antioxidant quercetin (QR) from the buds of Sophora Japanese (Sophora japonica L.) using the subcritical water (SBW). For the first time, SBW that serves as a reactant and a solvent has been used to obtain QR in good yields starting from the buds of Sophora Japanese. High-performance liquid chromatography was used to determine the quantitative and qualitative compositions of the obtained products. For the first time, a new eco-friendly “one-pot” technique was proposed for production of QR from the buds of Sophora Japanese using SBW. This method of preparation of QR allows one to avoid the use of toxic organic solvents. The good yields of the targeted QR can be obtained for the period of time which is ten times shorter than needed by the traditional procedures.

Keywords: Flowers buds, One-pot, quercetin, Sophora Japanese, Subcritical water Introduction.

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