Praveen R Shahapur1, BV Peerapur1, RP Shahapur2, RM Honnutagi2, MS Biradar2
1 Department of Microbiology, BLDE University’s Shri. B. M. Patil Medical College, Bijapur, Karnataka, India
2 Department of Medicine, BLDE University’s Shri. B. M. Patil Medical College, Bijapur, Karnataka, India
Nocardia otitidiscaviarum is a rare clinical isolate of primary cutaneous infections. This report describes a case of lymphocutaneous nocardiosis caused by N. otitidiscaviarum. Analysis of 16S ribosomal RNA gene of the isolate and the type strain of N. otitidiscaviarum DSM 43242 showed 100% similarity. The partial gene sequence of 1439 bp was submitted to GenBank. (EU031786). The isolate was susceptible only to amikacin, minocycline, linezolid and resistant to remaining other routine anti-nocardial drugs. The patient was free of nocardiosis after 12 weeks of treatment with amikacin and linezolid. We reviewed four other cases of lymphocutaneous nocardiosis caused by N. otitidiscaviarum.
Keywords: 16S ribosomal RNA genes, linezolid, lymphocutaneous nocardiosis, nocardia otitidiscaviarum