Candida Vaz1, Richa Bharti1, Rashi Gupta1, Priyatama Pandey1, Hafiz Ahmed2, Lalit Kumar3, Ritu Kulshreshtha4, Alok Bhattacharya5
1School of Computational and Integrative Sciences; Jawaharlal Nehru University; New Delhi- 110067, India.
2School of Life Sciences Jawaharlal Nehru University; New Delhi-110016, India.
3Department of Medical Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Science, New Delhi, India.
4Department of Biochemical Engineering and Biotechnology; Indian Institute of Technology; New Delhi-110067, India.
5School of Computational and Integrative Sciences; Jawaharlal Nehru University; New Delhi- 110067; School of Life Sciences Jawaharlal Nehru University; New Delhi-110016, India.
MicroRNAs have been recognized as one of the key regulatory non coding RNAs that are involved in a number of basic cellular processes and are also thought to be a useful biological marker for disease state, such as cancer. Next generation or deep sequencing of total small RNAs is helping microRNA discovery and profiling and has led to identification of a number of differentially regulated functionally important miRNAs, both known and novel. Chronic myelogenous leukemia (CML) is a form of myeloproliferative disorder that is more common in adults and affects a number people throughout the world. Identification of suitable diagnostic and prognostic markers based on miRNAs would help in treatment of this disease. Read More…