Remya Paul1, JK Mukkadan2
1Department of Physiology, Little Flower Hospital and Research Centre, Angamaly, Kerala, India.
2Little Flower Hospital and Research Centre, Angamaly, Kerala, India.
Introduction: Prediabetes is the state of intermediate hyperglycemia. The present study was conducted to analyze the effect of controlled vestibular stimulation (CVS) on blood glucose levels, oxidative stress, and anxiety levels in prediabetic patients. Materials and Methods: This randomized controlled study was conducted at Little Flower Hospital and Research Centre, Angamaly, Kerala. This study comprised 117 prediabetic patients divided into experimental and control groups. Anthropometric measurements, blood pressures, blood glucose levels, and oxidative stress parameters were estimated. State-Trait Anxiety Inventory questionnaire was used to measure the anxiety levels. CVS was provided to the patients in the experimental group using a swing with back to front direction for 3 months. The parameters were reassessed after 3 months of intervention. Comparisons of parameters were carried out by paired t-test, Wilcoxon signed-rank test, and multivariate regression analysis. Results: Blood glucose levels, malondialdehyde level, and anxiety levels were significantly decreased in the experimental group compared to the control group. There was a significant increase in the superoxide dismutase activity after the intervention compared with the control group. Conclusion: The present study confirmed the importance of cost-effective lifestyle intervention for prediabetic patients. CVS can be incorporated in the lifestyle to maintain optimum blood glucose levels and tackle oxidative stress and anxiety.
Keywords: Anxiety, oxidative stress, prediabetes, vestibular stimulation.