Manu Mangal1, Dhwani Raghav2, Vinay Sharma3, Subhash Mohan Agarwal1
1Bioinformatics Division, Institute of Cytology and Preventive Oncology (icmr), I-7, sector-39, Noida-201301, India.
2Bioinformatics Division, Institute of Cytology and Preventive Oncology (icmr), I-7, sector-39, Noida-201301; Department of Bioscience and Biotechnology, Banasthali University, Rajasthan 304022, India.
3Department of Bioscience and Biotechnology, Banasthali University, Rajasthan 304022, India.
ABSTRACT
Cervical cancer, the malignant neoplasm of the cervix uteri is the second most common cancer among women worldwide and the top most cancer in India. Several risk factors have been shown to alter the expression of genes responsible for the diseased state. One of the key mechanisms by which gene expression is controlled is transcriptional regulation, which is mediated through transcription factors (TFs). Therefore, it is important to decipher and analyze TFs that bind to regulatory regions of diseased genes and determine their expression. Read More …
