Manas Bajpai1, Deshant Agarwal1, Anindya Bhalla2, RM VatchalaRani3, Malay Kumar4
1 Department of Oral and Maxillofacial Pathology, National Institute of Medical Sciences Dental College, Jaipur, India
2 Department of Public Health Dentistry, National Institute of Medical Sciences Dental College, Jaipur, India
3 Departmens of Oral and Maxillofacial Pathology, Faculty of Dentistry, Jamiya Miliya Islamiya University, Delhi, India
4 Department of Oral and Maxillofacial Pathology, Ahmedabad Dental College, Ahmedabad, India
Oral lichen planus (OLP) is a mucocutaneous disease with well-established clinical and histopathological features. It has a prevalence of approximately 1%. The etiopathogenesis is poorly understood. The annual malignant transformation is less than 0.5%. There are no effective means to either predict or to prevent such event. Clinically, OLP present as bilateral symmetrical lesion and hence lichen planus isolated to a single oral site other than the gingiva is very uncommon. On the other hand lichenoid reaction (LR) are the lesions which are similar clinically and histopathologically with OLP, but they are induced with some drug reaction and usually they do not show bilateral pattern like lichen planus. We reported a very uncommon case of unilateral lichen planus which was clinically diagnosed as LR, but in the absence of any cause-effective relationship biopsy was taken for histopathological examination Histopathologically, LR cannot be differentiated with OLP, so the final diagnosis was made on the immunohistochemical ground.
Keywords: Immunohistochemistry, lichenoid reaction, oral lichen planus, unilateral