Moulisha Biswas1, Pallab Kanti Haldar2, Ashoke Kumar Ghosh3
1Bengal Institute of Pharmaceutical Sciences, Kalyani, Nadia, India.
2Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India.
3Bengal School of Technology, Delhi Road, Sugandha, Hooghly, India.
This study evaluated the in vitro antioxidant potential of petroleum ether (60-80°C), chloroform, and methanol extract of the fruits of Dregea volubilis Benth (Asclepiadaceae). The different antioxidant assays, including total antioxidant activity, reducing power, free radical, super oxide anion radical, nitric oxide scavenging, lipid peroxidation, and total phenolic content were studied. The extracts exhibited potent total antioxidant activity that increased with increasing amount of extract concentration, which was compared with standard drug vitamin C at different concentrations as extracts. The different concentrations of all the extracts and vitamin C showed inhibition on lipid peroxidation. In addition, all the extracts had effective reducing power, free radical scavenging, super oxide anion scavenging, nitric oxide scavenging, lipid peroxidation, and total phenolic content depending on concentration. These various antioxidant activities were compared with standard antioxidant such as vitamin C at different concentration as different extracts.
Keywords: Dregea volubilis , free-radical scavenging, in vitro antioxidant.