Ankita Tandon1, Narendra Nath Singh2, Gadiputi Sreedhar2
1Department of Oral Pathology and Microbiology, Jamia Millia Islamia, New Delhi, India.
2Kothiwal Dental College and Research Centre, Moradabad, India.
Introduction: Reduction of functioning minor salivary glands may contribute to emergence of mucosal infections, mucosal ulceration, and possibly dental caries. A study was, therefore, designed to understand the exact role of minor salivary gland secretions over dental caries. Methodology: We studied the average labial distribution of functional minor salivary glands using various pre-defined locations, counted the minor salivary gland secretion imprints, and correlated the decayed missing filledlevels in subjects. The functional level and amount of secretion of minor salivary gland were evaluated. The radial immunodiffusion was performed by Diffu-Plate kit and the dimensions of the ring were correlated with the amount of immunoglobulin A in saliva. Results: The mean number of functional labial minor salivary glands, amount of secretion, level of glycoprotein secretion, and immunoglobulin A secretion levels could very well dictate the functional status and role of minor salivary glands over caries assessment. Conclusion: The above-mentioned tests could be of major significance in routine diagnosis of the most common oral disease, i.e., dental caries.
Keywords: Radial immunodiffusion, salivary immunoglobulin A, unstimulated whole saliva.