Molecular modeling studies of hypermodified nucleosides present in anticodon loop of tRNA

Molecular modeling studies of hypermodified nucleosides present in anticodon loop of tRNA

May 26, 2012

Navanath M Kumbhar1, Bajarang V Kumbhar2, Kailas D Sonawane31Department of Biotechnology, Shivaji University, Kolhapur – 416 004, (M.S.), India.2Structural Bioinformatics Unit, Department of Biochemistry, Shivaji University, Kolhapur -416 004, (M.S.), India.3Structural Bioinformatics Unit, Department of Biochemistry and Microbiology, Shivaji University, Kolhapur –…

Sequence and structural analysis enables prediction of functionally important residues responsible for regulating Epidermal Growth Factor Receptor tyrosine kinase activity

Sequence and structural analysis enables prediction of functionally important residues responsible for regulating Epidermal Growth Factor Receptor tyrosine kinase activity

May 26, 2012

Subhash Mohan AgarwalBioinformatics Division, Institute of Cytology and Preventive Oncology (icmr), I-7, sector-39, Noida-201301, India. ABSTRACT Protein tyrosine kinases, which are responsible for development of many cancers, have emerged as a major class of drug targets in recent years. Among them, one…

Proteomic study to investigate the role of sulphur in Cd stressed Arabidopsis thaliana

Proteomic study to investigate the role of sulphur in Cd stressed Arabidopsis thaliana

May 26, 2012

Humayra Bashir, Javed Ahmad, Rita Bagheri, M Irfan QureshiProteomics & Bioinformatics Lab, Department of Biotechnology, Jamia Millia Islamia, New Delhi-100 025, India. ABSTRACT The changes induced in leaf proteome and thylakoidal Multi-protein complexes (MPCs) of Arabidopsis thaliana (Col- 0) exposed to cadmium…

microRNA mediated regulation of plant secondary metabolism: An In silico analysis

microRNA mediated regulation of plant secondary metabolism: An In silico analysis

May 26, 2012

Vidushi Mahajan1, Anuj Mahajan2, Sandeep Singh Pagoch1, Yashbir S Bedi1, Sumit G Gandhi11Plant Biotechnology Division, Indian Institute of Integrative Medicine (IIIM-CSIR), Canal Road, Jammu – 180 001, India.2School Of Computer Science Engineering, Shri Mata Vaishno Devi University, J&K – 182320, India. ABSTRACT…

The computational-based structure of Dwarf 14 provides evidence for its role as potential strigolactone receptor in plants

The computational-based structure of Dwarf 14 provides evidence for its role as potential strigolactone receptor in plants

May 26, 2012

Noura Gaiji1, Francesca Cardinale2, Cristina Prandi3, Paola Bonfante4, Graziella Ranghino11Geol sas, Vercelli, Italy.2Dipartimento di Colture Arboree, Università di Torino, Italy.3Dipartimento di Chimica Generale e Chimica Organica, Università di Torino, Italy.4Dipartimento di Biologia Vegetale, Università di Torino, Italy. ABSTRACT Strigolactones (SLs) are recently…

In silico characterization of PFCYC-1, A cyclin homologue of Plasmodium falciparum

In silico characterization of PFCYC-1, A cyclin homologue of Plasmodium falciparum

May 26, 2012

Dinesh GuptaInternational centre for genetic engineering and biotechnology, Aruna Asaf Marg, New Delhi, India. ABSTRACT Malaria is still one of the deadly disease resulting in the death of million of people worldwide and situation has become worse due to antimalarial drug resistance….

A survey on recent developments in comparison of protein structure methods

A survey on recent developments in comparison of protein structure methods

May 26, 2012

KM Prakash Lingam1, S Chandrakala21Anna University of Technology, Chennai, India.2Dept. of Computer Science, Velammal Engineering College, Chennai, India. ABSTRACT Comparison of protein structures is an important tool for understanding the evolutionary relationships between proteins, predicting protein structures and thereby possibly predicting protein…

In silico structural analysis of a Brassica juncea sequence containing kinase specific domain

In silico structural analysis of a Brassica juncea sequence containing kinase specific domain

May 26, 2012

Javed Ahmad1, Mirza Sarwar Baig1, Irfan Qureshi1, Gohar Taj21Department of Biotechnology, Jamia Millia Islamia, New Delhi, India.2Department of Molecular Biology and Genetic Engineering, G.B. Pant University of Agriculture & Technology, Pantnagar, India. ABSTRACT Protein kinase is a enzyme that modifies other proteins…

Prediction and classification of critical residues into fold and function using an information theoretic method

Prediction and classification of critical residues into fold and function using an information theoretic method

May 26, 2012

Mohd Rehan, Andrew M LynnJawaharlal Nehru University, New Delhi, India. ABSTRACT The residue conservation in a multiple alignment of a protein and its homologues indicates the importance of the residue for maintaining the structure and function of the protein. Often, the mutational…

Isozyme specific changes in antithrombin structure forms the basis of its improved heparin binding for anticoagulant activity

Isozyme specific changes in antithrombin structure forms the basis of its improved heparin binding for anticoagulant activity

May 26, 2012

Poonam Singh, Khushboo Singh, Mohamad Aman JairajpuriProtein Conformation and Enzymology Lab, Department of Biosciences, Jamia Millia Islamia, New Delhi-110025, India. ABSTRACT Antithrombin III (ATIII) is the main inhibitor of the coagulation proteases like factor Xa and thrombin. Anticoagulant activity of ATIII is…