MN Palaksha1, Mansoor Ahmed2, Sanjoy Das1
1Aditya Institute of Pharmaceutical Sciences and Research, A.D.B. Road, Aditya Nagar, Surampalem, East Godavari District, Andhra Pradesh, India.
2Department of Pharmacology, Sri Siddaganga College of Pharmacy, B. H. Road, Tumkur, Karnataka, India.
This study focuses the significant antibacterial activity of Garlic (Allium sativum Linn.) extract on streptomycin-resistant strains solely and in synergism with streptomycin. Gram-positive Staphylococcus aureus ATCC BAA 1026 and gram-negative Escherichia coli ATCC 10536 were made resistant to standard antibiotic streptomycin used as a control in the experiment. Zones of inhibition of different treatment groups were measured by agar-well-diffusion assay and compared with control. Statistical comparison of sole extract and streptomycin synergism with streptomycin control had proved it significant.
Keywords: Antibacterial, antibiotic, Escherichia coli, resistance, Staphylococcus aureus, synergism.