Analysis of annotation strategies for hypothetical proteins: A case study of Neisseria

Analysis of annotation strategies for hypothetical proteins: A case study of Neisseria

May 26, 2012

Neeraj Nagpal, Neera Munjal, Sayan ChatterjeeUniversity School of Biotechnology, Guru Gobind Singh Indraprastha University, New Delhi, India. ABSTRACT Growing possibilities of biotechnology for genome sequencing lead to generation of sequences for millions of genes. However, function of majority of these genes is…

Community and functional analysis of metagenome data from hot spring

Community and functional analysis of metagenome data from hot spring

May 26, 2012

Mansi B Parmar, Rajesh K PatelHemchandracharya North Gujrat University, Patan, India. ABSTRACT Metagenomics is the culture-independent genomics analysis of microbial communities. “Metagenomics” describes the functional and sequence-based analysis of the collective microbial genomes contained in an environmental sample. With development of the…

Identification and analysis of biomarkers for mismatch repair proteins: A bioinformatics approach

Identification and analysis of biomarkers for mismatch repair proteins: A bioinformatics approach

May 26, 2012

Manika Sehgal, Tiratha Raj SinghDepartment of Biotechnology and Bioinformatics, Jaypee University of Information and Technology (JUIT), Waknaghat, Solan-173234, H.P., India. ABSTRACT Mismatch repair is a highly conserved process from prokaryotes to eukaryotes. The first evidence for mismatch repair was obtained from S….

A central repository for functional and evolutionary information of human proteins

A central repository for functional and evolutionary information of human proteins

May 26, 2012

Inderjit Singh Yadav, Dhwani Raghav, Subhash Mohan AgarwalBioinformatics Division, Institute of Cytology and Preventive Oncology (icmr), I-7, Sector-39, Noida-201301, India. ABSTRACT Evolution is a natural phenomenon occurring in nature that creates pressure on the organism for its survival. Evolutionary novelties are brought…

In silico analysis of hemagglutinin, neuraminidase, and matrix protein- A comparative study on different strains of H5n1 virus

In silico analysis of hemagglutinin, neuraminidase, and matrix protein- A comparative study on different strains of H5n1 virus

May 26, 2012

Subhomoi BorkotokyCentre for bioinformatics, Pondicherry University, Pondicherry, India. ABSTRACT Pandemic influenza virus has its origins in avian influenza viruses. The highly pathogenic avian influenza virus subtype H5N1 is already panzootic in poultry, with attendant economic consequences. It continues to cross species barriers…

Comparative genomic strategy in human disease genes

Comparative genomic strategy in human disease genes

May 26, 2012

Sayan ChatterjeeUniversity School of Biotechnology, Guru Gobind Singh Indraprastha University, New Delhi, India. ABSTRACT DNA repair genes encode proteins that protect organisms against genetic damage generated by environmental agents and by-products of cell metabolism. The importance of these genes in life maintenance…

Functional diversity in the Enolase superfamily proteins

Functional diversity in the Enolase superfamily proteins

May 26, 2012

Kaiser Jamil1, M Sabeena21Bhagwan Mahavir Medical Research Centre, Mahavir Marg, Hyderabad – 500 004, A.P.; School of Life Sciences (SLS), Jawaharlal Nehru Institute of Advanced Studies, (JNIAS), Secunderabad-500 003, India.2Research Associate, Centre for Biotechnology and Bioinformatics- (CBB), Jawaharlal Nehru Institute of Advanced…

Molecular modeling studies of hypermodified nucleosides present in anticodon loop of tRNA

Molecular modeling studies of hypermodified nucleosides present in anticodon loop of tRNA

May 26, 2012

Navanath M Kumbhar1, Bajarang V Kumbhar2, Kailas D Sonawane31Department of Biotechnology, Shivaji University, Kolhapur – 416 004, (M.S.), India.2Structural Bioinformatics Unit, Department of Biochemistry, Shivaji University, Kolhapur -416 004, (M.S.), India.3Structural Bioinformatics Unit, Department of Biochemistry and Microbiology, Shivaji University, Kolhapur –…

Sequence and structural analysis enables prediction of functionally important residues responsible for regulating Epidermal Growth Factor Receptor tyrosine kinase activity

Sequence and structural analysis enables prediction of functionally important residues responsible for regulating Epidermal Growth Factor Receptor tyrosine kinase activity

May 26, 2012

Subhash Mohan AgarwalBioinformatics Division, Institute of Cytology and Preventive Oncology (icmr), I-7, sector-39, Noida-201301, India. ABSTRACT Protein tyrosine kinases, which are responsible for development of many cancers, have emerged as a major class of drug targets in recent years. Among them, one…

Proteomic study to investigate the role of sulphur in Cd stressed Arabidopsis thaliana

Proteomic study to investigate the role of sulphur in Cd stressed Arabidopsis thaliana

May 26, 2012

Humayra Bashir, Javed Ahmad, Rita Bagheri, M Irfan QureshiProteomics & Bioinformatics Lab, Department of Biotechnology, Jamia Millia Islamia, New Delhi-100 025, India. ABSTRACT The changes induced in leaf proteome and thylakoidal Multi-protein complexes (MPCs) of Arabidopsis thaliana (Col- 0) exposed to cadmium…