The emerging assembly line of genomes to hit molecules In silico

The emerging assembly line of genomes to hit molecules In silico

May 26, 2012

B JayaramDepartment of Chemistry & Kusuma School of Biological Sciences & Supercomputing Facility for Bioinformatics & Computational Biology, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi-110016, India. ABSTRACT Recent advances in genome sequencing projects and the concurrent developments in scientific softwares…

In silico analysis and expression of multiple novel splice variants of PKA catalytic beta subunit gene in mouse

In silico analysis and expression of multiple novel splice variants of PKA catalytic beta subunit gene in mouse

May 26, 2012

Tarique Sarwar, Abdul Rouf Banday, Mohammad TabishDepartment of Biochemistry, Faculty of Life Sciences, A.M. University, Aligarh, 202002, India. ABSTRACT PKA (Protein Kinase-A) is a second messenger-dependent enzyme that has been implicated in a wide range of cellular processes, including transcription, metabolism, cell…

Basal core promoter (BCP) mutations with respect to hepatitis B virus genotypes and serologic status

Basal core promoter (BCP) mutations with respect to hepatitis B virus genotypes and serologic status

May 26, 2012

Masarrat Afroz, Sabihur Rahman Farooqui, Zaheenul Islam Siddiqui, Syed Ali Azam, Syed Naqui KazimCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi-110025, India. ABSTRACT The region spanning from the nucleotide 1742 to 1849 within the 3.2kb hepatitis B virus…

Sequence, structure and function of microtubule affinity-regulating kinase: An enzyme plays potential role in cell division

Sequence, structure and function of microtubule affinity-regulating kinase: An enzyme plays potential role in cell division

May 26, 2012

Farha Naz, Faizan Ahmad, Md. Imtaiyaz HassanCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India. ABSTRACT Microtubule affinity-regulating kinase (MARK) is a Ser/Thr kinase, which phosphorylates tubulin binding domain (KXGS motifs in the repeat domain)…

Evolution of homeobox protein sequence (Hoxa9) across different species using phylogenetic analysis and expression analysis of the sequence in reference to the occurrence of Acute Myeloid Leukemia

Evolution of homeobox protein sequence (Hoxa9) across different species using phylogenetic analysis and expression analysis of the sequence in reference to the occurrence of Acute Myeloid Leukemia

May 26, 2012

Priyanka Narad1, Abhishek Sengupta1, Gulshan Wadhwa21Amity University, Noida, India.2Apex Biotechnology Information Center, Department of Biotechnology, Ministry of Science & Technology, New Delhi, India. ABSTRACT Cytogenetic, genetic and functional studies have demonstrated a direct link between deregulated Hoxa9 expression and acute myeloid leukemia…

A comprehensive analysis of isomirs and their targets using high-throughput sequencing data for Arabidopsis thaliana

A comprehensive analysis of isomirs and their targets using high-throughput sequencing data for Arabidopsis thaliana

May 26, 2012

Firoz Ahmed, Patrick Xuechun ZhaoBioinformatics Laboratory, Plant Biology Division, Samuel Roberts Noble Foundation, Ardmore, Oklahoma 73401, USA. ABSTRACT The roles of microRNAs (miRNAs) in gene regulation have been well recognized. Recent establishment of large-scale high-throughput small RNA sequencing projects, such as the…

Computational analysis of cotton mirnas targeting genome of Cotton leaf curl Multan Virus and associated satellite DNA

Computational analysis of cotton mirnas targeting genome of Cotton leaf curl Multan Virus and associated satellite DNA

May 26, 2012

M Sarwar Baig, Shweta, Jawaid A KhanPlant Virology Lab, Department of Biosciences, Faculty of Natural Sciences, Jamia Millia Islamia, New Delhi-110025, India. ABSTRACT Cotton leaf curl Multan virus (CLCuMV), genus Begomovirus, family Gemnivirdae is the most devastating virus attributed to huge losses…

Amino acid sequence analysis of thermostable endo-ß-1, 4-glucanase purified from Trichoderma viride

Amino acid sequence analysis of thermostable endo-ß-1, 4-glucanase purified from Trichoderma viride

May 26, 2012

Nidhee ChaudharyAmity Institute of Biotechnology, Amity University, Sector-125, Noida-201303, Uttar Pradesh, India. ABSTRACT In the present investigation amino acid sequence analysis of thermostable endo-ß-1, 4-glucanase purified from Trichoderma viride is being reported. The purified enzyme was found to be thermostable up to…

Computational analysis of regulatory elements

Computational analysis of regulatory elements

May 26, 2012

Shivesh GhuraJaypee Institute of Information Technology University, Sector 62 Noida, Uttar Pradesh 201307, India. ABSTRACT With the advent of highthroughput technology, the compilation of multiple metazoan genome sequences and large scale expression data available on various databases, these genome sequences are yet…

Computational prediction and identification of new splice variant of PKA catalytic alpha subunit gene in mouse

Computational prediction and identification of new splice variant of PKA catalytic alpha subunit gene in mouse

May 26, 2012

Mohammad Aamir Hussain, Abdul Rouf Banday, Mohammad TabishDepartment of Biochemistry, Faculty of Life Sciences, A.M. University, Aligarh, U.P. 202002, India. ABSTRACT Cyclic AMP-dependent protein kinase (PKA) is a holoenzyme that consists of two regulatory and two catalytic subunits each encoded by separate…