Frank EisenhaberDirector – Bioinformatics Institute (BII) Agency for Science, Technology and Research (A*STAR) 30 Biopolis Street #07-01, Matrix Building, 138671, Singapore. ABSTRACT Although life sciences are not truly an area of theoretical research, there are important niches where non-experimental efforts can make…

Sudhir Kumar1, Isha Raj1, Isha Nagpal1, N Subbarao2, S Gourinath11School of Life Sciences, Jawaharlal Nehru University, New Delhi-110067, India.2School of computational and integrative sciences, Jawaharlal Nehru University, New Delhi-110067, India. ABSTRACT Cysteine (cys) plays a major role in growth and survival of…

Jooyoung LeeCenter for In Silico Protein Science & School of Computational Sciences, Korea Institute for Advanced Study, 85 Hoegiro, Dongdaemun-gu, Seoul 130-722, Korea ABSTRACT One of the fundamental goals of modern sciences is to understand the nature of life, and deciphering the…

Kenji MizuguchiNational Institute of Biomedical Innovation, 7-6-8 Asagi-Saito, Ibaraki-City, Osaka, 567-0085, Japan ABSTRACT We have recently developed TargetMine, an integrated data warehouse for assisting drug discovery (http://targetmine.nibio.go.jp) and proposed an interactive method for target prioritization [1]. Target Mine and other computational biology…

Mirana Ramialison, Romaric Bouveret, Tram Doan, Danielle de Jong, Nicole Schonrock, Richard P HarveyThe Victor Chang Cardiac Research Institute, Sydney, Australia ABSTRACT The heart is a complex organ which successful develop­ment relies in part on complex feedback loops and cross-regulation between cardiac…

Shailza SinghNational Centre for Cell Science, NCCS Complex, Pune University Campus, Pune 411007, India. ABSTRACT Computational systems biology aims to develop a class of integrated mathematical, computational and experimental techniques with the goal of linking the knowledge of different molecular parts of…

D SundarIndian Institute of Technology (IIT) Delhi, New Delhi, India. ABSTRACT A technology for specifically targeting genes of humans has been the ‘Holy Grail’ in genetic medicine. The modular structure of zinc finger domain and modular recognition by zinc finger proteins make…

R SankararamakrishnanDepartment of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, U. P., India. ABSTRACT Apoptosis is an important physiological process in which unnecessary and malfunctioning of the cells are removed in a controlled and regulated fashion in multicellular organisms. The…

B JayaramDepartment of Chemistry & Kusuma School of Biological Sciences & Supercomputing Facility for Bioinformatics & Computational Biology, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi-110016, India. ABSTRACT Recent advances in genome sequencing projects and the concurrent developments in scientific softwares…

Shandar AhmadNational Institute of Biomedical Innovation, 7-6-8 Asagi-Saito, Ibaraki-City, Osaka, 567-0085, Japan. ABSTRACT All biological functions can ultimately be described in terms of interactions between proteins, nucleic acids and other smaller molecules. Molecular interactions provide for the enormous complexity of events in…