Dehydration-responsive functional association network of nuclear proteins in rice (Oryza sativa L.) reveals conserved and novel pathways

Dehydration-responsive functional association network of nuclear proteins in rice (Oryza sativa L.) reveals conserved and novel pathways

May 26, 2012

Niranjan ChakrabortyNational Institute of Plant Genome Research, Aruna Asaf marg, New Delhi, India. ABSTRACT Water-deficit or dehydration is the most crucial environmental factor that adversely affects most crop species and reduces crop yield worldwide. Therefore, understanding the molecular mechanism of dehydration response…

Epitope mapping and motif analysis of omp 28 gene of Salmonella typhi

Epitope mapping and motif analysis of omp 28 gene of Salmonella typhi

May 26, 2012

Anjani Saxena, Shantanu Tamuly, MK SaxenaAnimal Biotechnology Center, Department of Veterinary Physiology &Biochemistry College of Veterinary Sciences and Animal Husbandary, G.B.P.U.A&T, Pantnagar-263145, Uttrakhand, India. ABSTRACT Typhoid is one of the most important diseases of human beings caused by Salmonella Typhi. There are…

Two novel alternatively spliced transcripts of Prkar 1b gene of mouse: Identification using a novel approach of In-silico and molecular biology techniques

Two novel alternatively spliced transcripts of Prkar 1b gene of mouse: Identification using a novel approach of In-silico and molecular biology techniques

May 26, 2012

Sayeed Ur Rehman, Abdul Rouf Banday, Mohammad TabishDepartment of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh, U.P. 202002, India. ABSTRACT Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme involved in the signalling pathway of the second messenger cAMP….

Identification, sequence and structural analysis of cathepsin L – like proteins in Drosophila melanogaster

Identification, sequence and structural analysis of cathepsin L – like proteins in Drosophila melanogaster

May 26, 2012

Sunil Kumar1, Rohit Farmer2, Andrew P Turnbull3, Niraj Kanti Tripathy4, Babu A Manjasetty51Institute of Life Sciences, Nalco Square, Bhubaneswar 751023, India.2Sam Higginbottom Institute of Agriculture, Technology and Sciences, Allahabad 211007, India.3Cancer Research Technology Ltd., Birkbeck College, University of London, London, WC1E 7HX,…

Spatial architecture of nucleotides in eukaryotic genomes

Spatial architecture of nucleotides in eukaryotic genomes

May 26, 2012

Charu Kapil1, Samrat Chatterjee2, Tahir Husain2, Mohamad Aman Jairajpuri3, Manickam Yogavel2, Amit Sharma21Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi 110 067; Department of Biosciences, Jamia Millia Islamia University, Jamia Nagar, New-Delhi 110 025, India.2Structural and…

The emerging assembly line of genomes to hit molecules In silico

The emerging assembly line of genomes to hit molecules In silico

May 26, 2012

B JayaramDepartment of Chemistry & Kusuma School of Biological Sciences & Supercomputing Facility for Bioinformatics & Computational Biology, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi-110016, India. ABSTRACT Recent advances in genome sequencing projects and the concurrent developments in scientific softwares…

In silico analysis and expression of multiple novel splice variants of PKA catalytic beta subunit gene in mouse

In silico analysis and expression of multiple novel splice variants of PKA catalytic beta subunit gene in mouse

May 26, 2012

Tarique Sarwar, Abdul Rouf Banday, Mohammad TabishDepartment of Biochemistry, Faculty of Life Sciences, A.M. University, Aligarh, 202002, India. ABSTRACT PKA (Protein Kinase-A) is a second messenger-dependent enzyme that has been implicated in a wide range of cellular processes, including transcription, metabolism, cell…

Basal core promoter (BCP) mutations with respect to hepatitis B virus genotypes and serologic status

Basal core promoter (BCP) mutations with respect to hepatitis B virus genotypes and serologic status

May 26, 2012

Masarrat Afroz, Sabihur Rahman Farooqui, Zaheenul Islam Siddiqui, Syed Ali Azam, Syed Naqui KazimCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi-110025, India. ABSTRACT The region spanning from the nucleotide 1742 to 1849 within the 3.2kb hepatitis B virus…

Sequence, structure and function of microtubule affinity-regulating kinase: An enzyme plays potential role in cell division

Sequence, structure and function of microtubule affinity-regulating kinase: An enzyme plays potential role in cell division

May 26, 2012

Farha Naz, Faizan Ahmad, Md. Imtaiyaz HassanCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India. ABSTRACT Microtubule affinity-regulating kinase (MARK) is a Ser/Thr kinase, which phosphorylates tubulin binding domain (KXGS motifs in the repeat domain)…

Evolution of homeobox protein sequence (Hoxa9) across different species using phylogenetic analysis and expression analysis of the sequence in reference to the occurrence of Acute Myeloid Leukemia

Evolution of homeobox protein sequence (Hoxa9) across different species using phylogenetic analysis and expression analysis of the sequence in reference to the occurrence of Acute Myeloid Leukemia

May 26, 2012

Priyanka Narad1, Abhishek Sengupta1, Gulshan Wadhwa21Amity University, Noida, India.2Apex Biotechnology Information Center, Department of Biotechnology, Ministry of Science & Technology, New Delhi, India. ABSTRACT Cytogenetic, genetic and functional studies have demonstrated a direct link between deregulated Hoxa9 expression and acute myeloid leukemia…