Structure-function relationship of Mitogen Activated Protein kinase signal interacting kinase (Mnk1), a potent tumorigenic protein

Structure-function relationship of Mitogen Activated Protein kinase signal interacting kinase (Mnk1), a potent tumorigenic protein

May 26, 2012

Khalid Anwar, Faizan Ahmad, Md. Imtaiyaz HassanCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia (Central University), Jamia Nagar, New Delhi 110 025, India. ABSTRACT MAP (Mitogen Activated Protein) kinase-interacting serine/threonine-protein kinase 1 (Mknk1 or Mnk1) is an important intermediate member…

Insilico study of the A 2A R-D 2 R kinetics and revelation of residues Involved at the interfacial surface for heteromerization

Insilico study of the A 2A R-D 2 R kinetics and revelation of residues Involved at the interfacial surface for heteromerization

May 26, 2012

Amresh Prakash, Pratibha Mehta, LuthraMedicinal Chemistry Division, Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, North Campus, Mall Road, Delhi 110007, India. ABSTRACT The structural and dynamic information of A 2A R-D 2 R could provide a more complete understanding…

Structural features of lysosmal proteins: A structure based analysis to understand the mechanism of lysosomal storage disease

Structural features of lysosmal proteins: A structure based analysis to understand the mechanism of lysosomal storage disease

May 26, 2012

Huma Naz, Faizan Ahmad, Md. Imtaiyaz HassanCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India. ABSTRACT Lysosomal storage diseases are occurs due to inherited deficiencies in various enzymes involved in basic metabolic processes. These enzymes…

Structure based function prediction of putative conserved proteins from Candida dubliniensis

Structure based function prediction of putative conserved proteins from Candida dubliniensis

May 26, 2012

Munazzah Tasleem, Seemi Kalam, Faizan Ahmad, Md. Imtaiyaz HassanCentre for Interdisciplinary Research in Basic Sciences, Jamia Nagar, New Delhi 110025, India. ABSTRACT Candida dubliniensis genome contains 8 chromosomes, 6095 gene sequences, 5860 protein coding sequences. Out of these 5860 protein coding sequences…

Three-dimensional structure prediction of putative conserved proteins from R. rickettsiae: An approach to function annotation

Three-dimensional structure prediction of putative conserved proteins from R. rickettsiae: An approach to function annotation

May 26, 2012

Sobia Zaidi, Faizan Ahmad, Md. Imtaiyaz HassanCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi-110025, India. ABSTRACT Rickettsia is a genus of motile, gram negative and non spore forming highly pleomorphic bacteria having many virulent genes. Due to these…

In Silico analysis of flexible loop domain’s conformational changes affecting BH3 cleft of Bcl-2 protein

In Silico analysis of flexible loop domain’s conformational changes affecting BH3 cleft of Bcl-2 protein

May 26, 2012

Pawan Kumar Raghav, Yogesh Kumar Verma, Gurudutta U GangenahalliStem Cell and Gene Therapy Research Laboratory, Institute of Nuclear Medicine and Allied Sciences (INMAS), Lucknow Road, Timarpur, Delhi-110054, India. ABSTRACT Besides four Bcl-2 homology (BH1, BH2, BH3 and BH4) domains, the flexible loop…

Validation of Bhageerath-H: A homology ab-intio hybrid web server for protein tertiary structure prediction

Validation of Bhageerath-H: A homology ab-intio hybrid web server for protein tertiary structure prediction

May 26, 2012

Munazzah Tasleem1, B Jayaram21Department of Computer Sciences, Jamia Millia Islamia, Delhi, India.2Indian Institute of Technology, Delhi, India. ABSTRACT To assess the accuracy of Bhageerath_H and to suggest improvement in it so as to take it to perfection where it gives the best…

Predicting the stability of protein using its atomic coordinates in Protein Data Bank (PDB)

Predicting the stability of protein using its atomic coordinates in Protein Data Bank (PDB)

May 26, 2012

Syed Ausaf Ali, Asimul Islam, Faizan AhmadCenter for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India. ABSTRACT If protein stability is defined as Gibbs free energy change (∆GD°) associated with the denaturation equilibrium, native (N) conformation↔structureless denatured (D) conformation…

Protein modeling studies for antibacterial drug target

Protein modeling studies for antibacterial drug target

May 26, 2012

Anjana Ghelani1, Pravin Dudhagara2, Bhoomi Patel3, Rajesh Patel31Department of lifesciences, Hemchandracharya North Gujarat University, Patan; Shree Ramkrishna Institute of Computer Education and applied sciences, Surat, Gujarat, India.2Department of lifesciences, Hemchandracharya North Gujarat University, Patan; Department of Biotechnology, VeerNarmad South Gujarat University, Surat,…