Rahul Agarwal, Swarnima Kumari, Vikrant Nain, Shakti SahiSchool of Biotechnology, Gautam Buddha University, Greater Noida-201310, India. ABSTRACT Malaria remains a widespread and devastating disease. The CDC estimates that there are 300-500 million cases of malaria each year and more than 1 million…
Madhur Mishra, Mohammed Haris SiddiquiDepartment of Biotechnology, Microbiology and Bioinformatics, Integral University, Lucknow- 226026, India. ABSTRACT The HIV-1 protease enzyme is conscientious for the post translational processing of the viral Gag and Gag-Pol polyproteins to yield the structural proteins. The necessity of…
Anita Dubey, Tanmay Sahu, Suchi SmitaThe Bioinformatica Solutions, Lucknow (U.P), India. ABSTRACT Telomeres are repeated TTAGGG sequences that stop chromosome ends from behaving as random breaks. The up regulation of tankyrase1 protein encoded by TANKS gene (at Chromosome 8, NC_000008.10 (9413445..9639856)) in Homo…
Biplab Bhattacharjee1, Priya Prakash1, Rukmini Jonnalagadda1, BM Arpitha1, Jhinuk Chatterjee1, V Krishna Murthy1, Jayadev Joshi21Department of Biotechnology, PES Institute of Technology, Bangalore, India.2Radiation Biosciences Group, Institute of Nuclear Medicine & Allied Sciences (INMAS) – DRDO, New Delhi, India. ABSTRACT New Delhi metallo…
Biplab Bhattacharjee1, Jhinuk Chatterjee1, Priya Jacob2, V Krishna Murthy11Department of Biotechnology, PES Institute of Technology, Bangalore, India.2RV College of Engineering, Bangalore, India. ABSTRACT NHelicobacter Pylori is a bacterium that causes a chronic low-level inflammation of the stomach lining and is strongly linked to…
Pooja BhardwajUniversity School of Biotechnology, GGSIP University, Dwarka Sec 16C, New Delhi, India. ABSTRACT Bioinformatics tools can help us to understand the computational design principles of drugs based on the structural knowledge of their target. It is possible to find a drug…
Amita Barik, C Nithin, P Manasa, Ranjit Prasad BahadurDepartment of Biotechnology, Indian Institute of Technology, Kharagpur 721302, India. ABSTRACT RNA plays a critical role in biological processes but due to limited knowledge of its structural model, the progress in protein-RNA docking is…
Richa AnandDepartment of Biochemical Engineering, Banaras Hindu university, UP, India. ABSTRACT Mycobacterium tuberculosis a causative agent of tuberculosis is gram-positive and slow growing bacterium. Decaprenyl-phosphoryl-β-D-ribose oxidase is an important enzyme involved in the cell wall synthesis of Mycobacterium tuberculosis. It is involved in…
Manika SehgalJUIT, Waknaghat, Solan, H.P., Shimla, India. ABSTRACT The current paper aims to design an in silico structure-based drug for treating the disease Schizophrenia. The word Schizophrenia (“split mind”) was coined by Eugen Bleuler in 1908.The disease manifests as abnormal thought processes, behaviour and…
Mukta Rani, Manas Ranjan Dikhit, Ganesh Chandra Sahoo, Pradeep DasBiomedical Informatics Division, Rajendra Memorial Research Institute of Medical Sciences, Agam Kuan, Patna 800007, India. ABSTRACT Visceral Leishmaniasis or Kala-azar is a protozoal parasitic devastating disease which takes a death toll of thousand of…
